Regenerative Medicine

Regenerative Medicine in Infertility

Regenerative medicine in infertility is a cutting-edge field that utilizes the body’s own healing and growth mechanisms to restore reproductive potential. One of the most promising techniques is Platelet-Rich Plasma (PRP) therapy, where a patient’s own platelets and growth factors are injected into reproductive tissues to enhance ovarian function, endometrial receptivity, and sperm quality.

At Jindal Hospital & Fertility Centre, under the expertise of Dr. Sunil Jindal and Dr. Anshu Jindal, we are among the pioneers in India offering PRP and other regenerative approaches in infertility. These therapies are especially valuable for patients with poor ovarian reserve, thin endometrium, repeated IVF failures, and certain cases of male infertility.

Indications for Regenerative Medicine in Infertility

In Women

• Poor ovarian reserve / Low AMH (Premature ovarian insufficiency)
• Thin endometrium resistant to conventional treatment
• Repeated IVF failures despite good-quality embryos
• Endometriosis-related infertility (adjunctive role)
• Perimenopausal infertility where ovarian response is declining

In Men

• Non-obstructive azoospermia (as adjunct to Micro-TESE)
• Severe oligoasthenoteratozoospermia (OAT)
• Sperm DNA fragmentation due to oxidative stress
• Erectile dysfunction & Peyronie’s disease (PRP + stem-cell based therapies)

How PRP Works in Infertility

Platelet-Rich Plasma (PRP) contains a high concentration of growth factors and cytokines that stimulate cellular repair, regeneration, and angiogenesis.

• In Ovaries: PRP infusion may activate dormant follicles, improve AMH levels, and increase oocyte yield during IVF.
• In Endometrium: PRP enhances blood supply, stem-cell recruitment, and endometrial thickness, improving embryo implantation rates.
• In Testes: PRP may reduce oxidative stress, improve microenvironment, and enhance spermatogenesis (currently under clinical studies).

PRP Procedure

1. Blood Collection: A small volume of the patient’s blood is drawn.
2. Centrifugation: Blood is processed to concentrate platelets and growth factors.
3. PRP Injection:
   • In Women: PRP is infused into the ovaries (ovarian rejuvenation) or uterine cavity (endometrial PRP).
   • In Men: PRP is injected into testes (experimental), penile tissues (for ED), or seminal vesicles.
4. Post-Procedure Monitoring: Patients can resume normal activities the same day; follow-up includes hormone and ultrasound monitoring.

Other Regenerative Approaches in Infertility

• Stem Cell Therapy: Under research for ovarian rejuvenation and spermatogenesis.
• Exosome Therapy: Experimental approach to improve follicular and endometrial function.
• Low-Level Laser Therapy (LLLT): Used to improve sperm motility and testicular function.

Why Choose Jindal Hospital & Fertility Centre?

• Pioneers in Regenerative Infertility Treatments in India: Among the first centers in India to introduce regenerative medicine approaches such as PRP and stem-cell based therapies for infertility.
• Global Expertise: Dr. Sunil Jindal has contributed internationally to regenerative and andrology research, bringing world-class knowledge and innovation to patient care.
• Integrated Approach: The centre combines regenerative therapies like PRP with advanced assisted reproductive technologies (ART) such as IVF, ICSI, and Micro-TESE for optimal outcomes.
• Proven Results: Documented success in challenging cases such as thin endometrium, low AMH, and repeated IVF failures.
• State-of-the-Art Facilities: PRP preparation and procedures are performed under sterile, laboratory-grade conditions using advanced equipment to ensure the highest safety and efficacy standards.
• Holistic Care: Every treatment plan integrates medical, surgical, and regenerative options tailored to each patient’s unique fertility needs and overall well-being.

Do’s & Don’ts for Patients Considering PRP

Do’s

• Consult a fertility expert before opting for PRP.
• Continue prescribed fertility medications as advised.
• Follow post-procedure instructions, including hydration, rest, and regular monitoring.
• Maintain a healthy lifestyle to support regenerative effects.

Don’ts

• Don’t consider PRP a guaranteed cure — it enhances fertility potential but doesn’t replace ART in all cases.
• Avoid unverified clinics or beauty centers offering “PRP for fertility” without medical expertise.
• Don’t skip follow-up appointments — monitoring AMH, FSH, and endometrial thickness is essential.
• Don’t delay conventional ART treatments when age is a critical factor.